BDBM19778 (2S)-2-(1-benzofuran-2-ylformamido)-4-methyl-N-[(4S,7R)-7-methyl-3-oxo-1-(pyridine-2-sulfonyl)azepan-4-yl]pentanamide::Azepan-3-one compound 10::CHEMBL203665
SMILES CC(C)C[C@H](NC(=O)c1cc2ccccc2o1)C(=O)N[C@H]1CC[C@@H](C)N(CC1=O)S(=O)(=O)c1ccccn1
InChI Key InChIKey=BWYBBMQLUKXECQ-GIVPXCGWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 19778
Affinity DataKi: 0.0410nM ΔG°: -14.0kcal/molepH: 5.5 T: 2°CAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
Affinity DataKi: 0.0630nMAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
Affinity DataKi: 0.0680nM ΔG°: -13.7kcal/molepH: 5.5 T: 2°CAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
TargetCathepsin K(Oryctolagus cuniculus (rabbit))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of rabbit cathepsin KMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of cathepsin B in human HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of cathepsin L in human HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of cathepsin S in human ramos cellsMore data for this Ligand-Target Pair