BDBM198176 2-((5-(4-Nitrophenylamino)-1,3,4-thiadiazol-2-yl)methyl)-5,6-diphenyl-1,2,4-triazin-3(2H)-one (4e)

SMILES [O-][N+](=O)c1ccc(Nc2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)s2)cc1

InChI Key InChIKey=WIWJJBQZCRGOAL-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 198176   

TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM198176(2-((5-(4-Nitrophenylamino)-1,3,4-thiadiazol-2-yl)m...)
Affinity DataKi:  880nMAssay Description:The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM198176(2-((5-(4-Nitrophenylamino)-1,3,4-thiadiazol-2-yl)m...)
Affinity DataIC50:  6.32E+4nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM198176(2-((5-(4-Nitrophenylamino)-1,3,4-thiadiazol-2-yl)m...)
Affinity DataIC50:  1.01E+3nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed