BDBM204923 phosphonoacetohydroxamate (PhAH)

SMILES ONC(=O)CP(O)(O)=O

InChI Key InChIKey=LDKRAXXVBWHMRH-UHFFFAOYSA-N

Data  3 IC50

PDB links: 6 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 204923   

TargetAlpha-enolase(Homo sapiens (Human))
University Of Texas M. D. Anderson Cancer Center

LigandPNGBDBM204923(phosphonoacetohydroxamate (PhAH))
Affinity DataIC50:  53.2nMpH: 7.4Assay Description:Enolase activity was measured by two different methods: a fluorometric NADH-linked assay or adirect spectrophotometric assay via formation of PEP. In...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-enolase(Homo sapiens (Human))
University Of Texas M. D. Anderson Cancer Center

LigandPNGBDBM204923(phosphonoacetohydroxamate (PhAH))
Affinity DataIC50:  51nMAssay Description:Inhibition of ENO1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-enolase(Homo sapiens (Human))
University Of Texas M. D. Anderson Cancer Center

LigandPNGBDBM204923(phosphonoacetohydroxamate (PhAH))
Affinity DataIC50:  62.3nMpH: 7.4Assay Description:Enolase activity was measured by two different methods: a fluorometric NADH-linked assay or adirect spectrophotometric assay via formation of PEP. In...More data for this Ligand-Target Pair