BDBM210750 US9290454, 3.2

SMILES OC(=O)CCCCc1cc2cc(ccc2c(=O)n1-c1ccc(F)cc1)C(=O)N[C@@H]1CCCc2cc(F)ccc12

InChI Key InChIKey=GMTWJEZQOQMIRZ-MUUNZHRXSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 210750   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM210750(US9290454, 3.2)
Affinity DataKi:  1.30nMAssay Description:Antagonist activity at CRTh2 (unknown origin) assessed as inhibition of CD11b activationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM210750(US9290454, 3.2)
Affinity DataKi:  6.5nMAssay Description:Antagonist activity at human CRTh2 expressed in HEK cells assessed as inhibition of DK-PGD2-mediated attenuation of forskolin-induced cAMP accumulati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM210750(US9290454, 3.2)
Affinity DataKi:  6.50nM ΔG°:  -12.1kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding was performed using filtration or scintillation proximity assay (SPA) technology. SPA assays were done at room temperature in 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent