BDBM220873 US9302986, 7

SMILES COc1cc(ccc1OCC(CN)=CF)C(=O)N(C)C

InChI Key InChIKey=PMMSHCNZOXUMKX-JXMROGBWSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 220873   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM220873(US9302986, 7)
Affinity DataIC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:Recombinant human MAO-B (0.06 mg/mL; Sigma Aldrich) was used as source of MAO-B enzyme activities. The assay was performed in a similar way as for hu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmiloride-sensitive amine oxidase [copper-containing](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM220873(US9302986, 7)
Affinity DataIC50: <1.00E+3nMpH: 7.4 T: 2°CAssay Description:Recombinant human DAO (2.4 μg/mL) was used as source of DAO enzyme activities. The assay was performed as described in the method for human SSAO/V...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM220873(US9302986, 7)
Affinity DataIC50: <1.00E+5nMpH: 7.4Assay Description:Briefly, HMEC cell expressing human SSAO/VAP-1 were grown in several 10 cm petri dishes, once the cells reached 100% confluency, cells were harvested...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent