BDBM22264 2,4,5-tri-substituted imidazole, 21l::{[(3R)-1-(3,4-dichlorophenyl)pyrrolidin-3-yl](methyl)sulfamoyl}({2-[5-(4-methoxyphenyl)-2-(thiophen-2-yl)-1H-imidazol-4-yl]ethyl})amine

SMILES [H][C@]1(CCN(C1)c1ccc(Cl)c(Cl)c1)N(C)S(=O)(=O)NCCc1[nH]c(nc1-c1ccc(OC)cc1)-c1cccs1

InChI Key InChIKey=CKFVZVGMTSXQFS-HXUWFJFHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22264   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Oryctolagus cuniculus (rabbit))
Bristol-Myers Squibb

LigandPNGBDBM22264(2,4,5-tri-substituted imidazole, 21l | {[(3R)-1-(3...)
Affinity DataIC50:  11nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed