BDBM22266 2,4,5-tri-substituted imidazole, 21n::{ethyl[(3R)-1-[1-(4-fluorophenyl)ethyl]pyrrolidin-3-yl]sulfamoyl}({2-[5-(4-methoxyphenyl)-2-(thiophen-2-yl)-1H-imidazol-4-yl]ethyl})amine

SMILES [H][C@]1(CCN(C1)C(C)c1ccc(F)cc1)N(CC)S(=O)(=O)NCCc1[nH]c(nc1-c1ccc(OC)cc1)-c1cccs1

InChI Key InChIKey=YCOQGGMZWKBBGI-UIDYPRJRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22266   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Oryctolagus cuniculus (rabbit))
Bristol-Myers Squibb

LigandPNGBDBM22266(2,4,5-tri-substituted imidazole, 21n | {ethyl[(3R)...)
Affinity DataIC50:  3nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed