BDBM223291 Pentostatin (PTN)

SMILES OC[C@H]1O[C@H](C[C@@H]1O)n1cnc2[C@H](O)CN=CNc12

InChI Key InChIKey=FPVKHBSQESCIEP-JQCXWYLXSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 223291   

TargetAdenosine deaminase(Streptomyces antibioticus)
Wuhan University

LigandPNGBDBM223291(Pentostatin (PTN))
Affinity DataKi:  1nM ΔG°:  -12.5kcal/molepH: 7.2 T: 2°CAssay Description:For the ADA activity assay, a reaction comprising 50 mM potassium phosphate buffer (pH 7.2), 0.1 mM Ara-A or adenosine, and 20 mg ADA was conducted a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine deaminase(Streptomyces antibioticus)
Wuhan University

LigandPNGBDBM223291(Pentostatin (PTN))
Affinity DataKi:  2.10nM ΔG°:  -12.0kcal/molepH: 7.2 T: 2°CAssay Description:For the ADA activity assay, a reaction comprising 50 mM potassium phosphate buffer (pH 7.2), 0.1 mM Ara-A or adenosine, and 20 mg ADA was conducted a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed