BDBM223460 US9320722, CD8

SMILES CCOC(=O)CN1C(=O)C(O)(CC(=O)c2ccncc2)c2ccccc12

InChI Key InChIKey=QSPBCAPOKXOTHX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 223460   

TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM223460(US9320722, CD8)
Affinity DataIC50:  800nMpH: 7.5Assay Description:IC50 values were determined for CB29 and its analogs using propionaldehyde as the substrate for ALDH1A1 and ALDH2 or benzaldehyde as the substrate fo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldehyde dehydrogenase, dimeric NADP-preferring(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM223460(US9320722, CD8)
Affinity DataIC50:  6.30E+3nMpH: 7.5Assay Description:IC50 values were determined for CB29 and its analogs using propionaldehyde as the substrate for ALDH1A1 and ALDH2 or benzaldehyde as the substrate fo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM223460(US9320722, CD8)
Affinity DataIC50:  1.11E+4nMpH: 7.5Assay Description:IC50 values were determined for CB29 and its analogs using propionaldehyde as the substrate for ALDH1A1 and ALDH2 or benzaldehyde as the substrate fo...More data for this Ligand-Target Pair
In DepthDetails US Patent