BDBM22357 1,3-Diarylprop-2-yn-1-one, 13n::1-(3,4-dimethoxyphenyl)-3-(4-methanesulfonylphenyl)prop-2-yn-1-one

SMILES COc1ccc(cc1OC)C(=O)C#Cc1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=OZHWLRKHAHPLNY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 22357   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Alberta

LigandPNGBDBM22357(1,3-Diarylprop-2-yn-1-one, 13n | 1-(3,4-dimethoxyp...)
Affinity DataIC50:  3.30E+3nMpH: 8.0 T: 2°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of Alberta

LigandPNGBDBM22357(1,3-Diarylprop-2-yn-1-one, 13n | 1-(3,4-dimethoxyp...)
Affinity DataIC50: >1.00E+4nMAssay Description:The lipoxygenase inhibitor screening assay detects and measures the hydroperoxides produced in the lipoxygenation reaction using a purified lipoxygen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoxygenase(Solanum tuberosum (potato))
University Of Alberta

LigandPNGBDBM22357(1,3-Diarylprop-2-yn-1-one, 13n | 1-(3,4-dimethoxyp...)
Affinity DataIC50:  1.00E+3nMAssay Description:The lipoxygenase inhibitor screening assay detects and measures the hydroperoxides produced in the lipoxygenation reaction using a purified lipoxygen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

LigandPNGBDBM22357(1,3-Diarylprop-2-yn-1-one, 13n | 1-(3,4-dimethoxyp...)
Affinity DataIC50: >1.00E+5nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed