BDBM223980 6,7-Dichloro-N-cyclopentylquinolin-4-amine (2)

SMILES Clc1cc2nccc(NC3CCCC3)c2cc1Cl

InChI Key InChIKey=CMPRHICRGYUFAI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 223980   

TargetHistone-lysine N-methyltransferase KMT5C(Homo sapiens (Human))
Abbvie

LigandPNGBDBM223980(6,7-Dichloro-N-cyclopentylquinolin-4-amine (2))
Affinity DataIC50:  1.20E+3nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase KMT5B(Homo sapiens (Human))
Abbvie

LigandPNGBDBM223980(6,7-Dichloro-N-cyclopentylquinolin-4-amine (2))
Affinity DataIC50:  590nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed