BDBM22421 (cyclohexylmethyl)[(1-phenyl-1H-indol-3-yl)methyl]amine::Indole compound 1b

SMILES C(NCc1cn(-c2ccccc2)c2ccccc12)C1CCCCC1

InChI Key InChIKey=RGRGORMCSWGRSY-UHFFFAOYSA-N

Data  1 IC50  2 ITC

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22421   

TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Novartis

LigandPNGBDBM22421((cyclohexylmethyl)[(1-phenyl-1H-indol-3-yl)methyl]...)
Affinity DataIC50:  700nMpH: 7.5 T: 2°CAssay Description:The IC50s of compounds were determined in the FRET assay, which was conducted as time-resolved measurement (TR-FRET) in a 1536 well plate format. The...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Activity Spreadsheet -- ITC Data from BindingDB

Found 2 hits for monomerid = 22421   

CellEstrogen-Related Receptor, alpha(Homo sapiens (Human))
Novartis

SyringePNGBDBM22421((cyclohexylmethyl)[(1-phenyl-1H-indol-3-yl)methyl]...)
ITC Data−TΔS°: 4.29kcal/mole ΔH°: -12.7kcal/mole logk: 1.30E+6
pH: 7.5 T: 25.00°C 
CellEstrogen-Related Receptor, alpha Mutant (C325S)(Homo sapiens (Human))
Novartis

SyringePNGBDBM22421((cyclohexylmethyl)[(1-phenyl-1H-indol-3-yl)methyl]...)
ITC Data−TΔS°: 4.69kcal/mole ΔH°: -13.0kcal/mole logk: 1.08E+6
pH: 7.5 T: 25.00°C