BDBM225520 GTC000228A::GTC000228B::GTC000228C

SMILES COCCCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3CNS(=O)(=O)c3c2)ncc1F

InChI Key InChIKey=ITEPKSLPXLETPN-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 225520   

TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225520(GTC000228A | GTC000228B | GTC000228C)
Affinity DataIC50:  2.45nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225520(GTC000228A | GTC000228B | GTC000228C)
Affinity DataIC50:  2.86nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225520(GTC000228A | GTC000228B | GTC000228C)
Affinity DataIC50:  2.07nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225520(GTC000228A | GTC000228B | GTC000228C)
Affinity DataIC50:  1.38nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225520(GTC000228A | GTC000228B | GTC000228C)
Affinity DataIC50:  3.35nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225520(GTC000228A | GTC000228B | GTC000228C)
Affinity DataIC50:  1.47nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225520(GTC000228A | GTC000228B | GTC000228C)
Affinity DataIC50:  2.08nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225520(GTC000228A | GTC000228B | GTC000228C)
Affinity DataIC50:  7nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225520(GTC000228A | GTC000228B | GTC000228C)
Affinity DataIC50:  4.35nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225520(GTC000228A | GTC000228B | GTC000228C)
Affinity DataIC50:  2.02nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225520(GTC000228A | GTC000228B | GTC000228C)
Affinity DataIC50:  5.36nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225520(GTC000228A | GTC000228B | GTC000228C)
Affinity DataIC50:  2nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225520(GTC000228A | GTC000228B | GTC000228C)
Affinity DataIC50:  3.66nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225520(GTC000228A | GTC000228B | GTC000228C)
Affinity DataIC50:  2.13nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225520(GTC000228A | GTC000228B | GTC000228C)
Affinity DataIC50:  1.10nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed