BDBM22775 3,5-di-tert-butylcyclohexa-3,5-diene-1,2-dione::Benzil-related compound, 54::cid_76915

SMILES CC(C)(C)C1=CC(=O)C(=O)C(=C1)C(C)(C)C

InChI Key InChIKey=NOUZOVBGCDDMSX-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 22775   

TargetLiver carboxylesterase 1(Homo sapiens (Human))
University Of Mississippi

LigandPNGBDBM22775(3,5-di-tert-butylcyclohexa-3,5-diene-1,2-dione | B...)
Affinity DataKi:  88.6nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Oryctolagus cuniculus (rabbit))
University Of Mississippi

LigandPNGBDBM22775(3,5-di-tert-butylcyclohexa-3,5-diene-1,2-dione | B...)
Affinity DataKi:  736nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Mississippi

LigandPNGBDBM22775(3,5-di-tert-butylcyclohexa-3,5-diene-1,2-dione | B...)
Affinity DataKi:  1.35E+3nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Mississippi

LigandPNGBDBM22775(3,5-di-tert-butylcyclohexa-3,5-diene-1,2-dione | B...)
Affinity DataKi: >1.00E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Mississippi

LigandPNGBDBM22775(3,5-di-tert-butylcyclohexa-3,5-diene-1,2-dione | B...)
Affinity DataKi: >1.00E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM22775(3,5-di-tert-butylcyclohexa-3,5-diene-1,2-dione | B...)
Affinity DataIC50:  9.84E+3nMpH: 7.4 T: 2°CAssay Description:The purpose of this assay is to identify non-competititve inhibitors of human PMI. This is accomplished by using a G6PD- NADPH-coupled assay. In the ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay