BDBM22842 1-dodecyl-2,3-dihydro-1H-indole-2,3-dione::CHEMBL222644::Isatin-based compound, 62

SMILES CCCCCCCCCCCCN1C(=O)C(=O)c2ccccc12

InChI Key InChIKey=GQEQKTGRIPEAKW-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 22842   

TargetCoagulation factor XII(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM22842(1-dodecyl-2,3-dihydro-1H-indole-2,3-dione | CHEMBL...)
Affinity DataKi:  8nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM22842(1-dodecyl-2,3-dihydro-1H-indole-2,3-dione | CHEMBL...)
Affinity DataKi:  10nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Oryctolagus cuniculus (rabbit))
St. Jude Research Hospital

LigandPNGBDBM22842(1-dodecyl-2,3-dihydro-1H-indole-2,3-dione | CHEMBL...)
Affinity DataKi:  88nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM22842(1-dodecyl-2,3-dihydro-1H-indole-2,3-dione | CHEMBL...)
Affinity DataKi: >1.00E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM22842(1-dodecyl-2,3-dihydro-1H-indole-2,3-dione | CHEMBL...)
Affinity DataKi: >1.00E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Doshisha Women'S College Of Liberal Arts

Curated by ChEMBL
LigandPNGBDBM22842(1-dodecyl-2,3-dihydro-1H-indole-2,3-dione | CHEMBL...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human Cdc25A phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed