BDBM231667 2-(3-(4-Chloropyridin-2-ylamino)phenoxy)-N-methylacetamide (2a)

SMILES CNC(=O)COc1cccc(Nc2cc(Cl)ccn2)c1

InChI Key InChIKey=CPVIJBMDWOGCHR-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 231667   

TargetPhenylalanine--tRNA ligase alpha/beta subunit(Pseudomonas aeruginosa)
Astrazeneca R&D Boston

LigandPNGBDBM231667(2-(3-(4-Chloropyridin-2-ylamino)phenoxy)-N-methyla...)
Affinity DataIC50:  8.20E+4nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231667(2-(3-(4-Chloropyridin-2-ylamino)phenoxy)-N-methyla...)
Affinity DataIC50:  1.40E+3nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed