BDBM233039 Finasteride (3)

SMILES CC(C)(C)NC(=O)C1CCC2C3CCC4NC(=O)C=C[C@]4(C)C3CC[C@]12C

InChI Key InChIKey=DBEPLOCGEIEOCV-USODZXNSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 233039   

TargetcDNA, FLJ78895, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Universidad Nacional Autonoma De Mexico

LigandPNGBDBM233039(Finasteride (3))
Affinity DataIC50:  8.5nMpH: 6.5 T: 2°CAssay Description:The reaction mixture contained a final volume of 1 mL: 1 mM dithiothreitol, sodium phosphate buffer 40 mM, at pH 6.5 for human prostate, 2 mM NADPH, ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed