BDBM233043 6-Chloro-3,20-dioxopregna-4,6-diene-17α-yl acetate (9)

SMILES CC(=O)O[C@@]1(CCC2C3C=C(Cl)C4=CC(=O)CC[C@]4(C)C3CC[C@]12C)C(C)=O

InChI Key InChIKey=QMBJSIBWORFWQT-GDMUWPLKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 233043   

TargetcDNA, FLJ78895, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Universidad Nacional Autonoma De Mexico

LigandPNGBDBM233043(6-Chloro-3,20-dioxopregna-4,6-diene-17α-yl ac...)
Affinity DataIC50:  19nMpH: 6.5 T: 2°CAssay Description:The reaction mixture contained a final volume of 1 mL: 1 mM dithiothreitol, sodium phosphate buffer 40 mM, at pH 6.5 for human prostate, 2 mM NADPH, ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed