BDBM237301 N-(2-cyanophenyl)-4-methylbenzenesulfonamide (6)

SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccccc1C#N

InChI Key InChIKey=AEWAFLUKJFIWDP-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 237301   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237301(N-(2-cyanophenyl)-4-methylbenzenesulfonamide (6))
Affinity DataKi:  602nM ΔG°:  -8.48kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237301(N-(2-cyanophenyl)-4-methylbenzenesulfonamide (6))
Affinity DataKi:  674nM ΔG°:  -8.41kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237301(N-(2-cyanophenyl)-4-methylbenzenesulfonamide (6))
Affinity DataIC50:  213nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237301(N-(2-cyanophenyl)-4-methylbenzenesulfonamide (6))
Affinity DataIC50:  1.82E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237301(N-(2-cyanophenyl)-4-methylbenzenesulfonamide (6))
Affinity DataIC50:  8.43E+3nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed