BDBM237304 N-(4-cyanophenyl)-4-methylbenzenesulfonamide (10)

SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)C#N

InChI Key InChIKey=HQQVYEMQVKDXJX-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 237304   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237304(N-(4-cyanophenyl)-4-methylbenzenesulfonamide (10))
Affinity DataKi:  519nM ΔG°:  -8.57kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237304(N-(4-cyanophenyl)-4-methylbenzenesulfonamide (10))
Affinity DataKi:  734nM ΔG°:  -8.36kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237304(N-(4-cyanophenyl)-4-methylbenzenesulfonamide (10))
Affinity DataIC50:  120nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237304(N-(4-cyanophenyl)-4-methylbenzenesulfonamide (10))
Affinity DataIC50:  1.48E+3nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237304(N-(4-cyanophenyl)-4-methylbenzenesulfonamide (10))
Affinity DataIC50:  1.23E+3nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed