BDBM237925 US9394285, 6

SMILES OC(=O)c1c[nH]c2cc(F)c(-c3ccc(cc3)C3(O)CCC3)c(F)c12

InChI Key InChIKey=VPUNMIRZXILGLE-UHFFFAOYSA-N

Data  1 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 237925   

LigandPNGBDBM237925(US9394285, 6)
Affinity DataEC50:  17.3nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM237925(US9394285, 6)
Affinity DataEC50:  35nMAssay Description:Allosteric activation of human AMPK alpha1/beta1/gamma1 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM237925(US9394285, 6)
Affinity DataKd:  20nMAssay Description:Binding affinity to human BAP-tagged AMPK alpha1/beta1/gamma1 by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed