BDBM239109 US10195181, Example 9::US9403810, 9

SMILES Cc1c(\C=C\C(C)(C)C)onc1C(=O)Nc1c(C)n(C)n(C2CCCCC2)c1=O

InChI Key InChIKey=DXVFLJBDMVFCLI-OUKQBFOZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 239109   

TargetE3 ubiquitin-protein ligase SMURF1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM239109(US10195181, Example 9 | US9403810, 9)
Affinity DataIC50:  58nMAssay Description:To determine the HECT E3 ligase selectivity of the compounds, a panel of biochemical HECT E3 ligase autoubiquitinylation assays was employed (Smurf-1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase SMURF1 [420-757](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM239109(US10195181, Example 9 | US9403810, 9)
Affinity DataIC50:  58nMT: 2°CAssay Description:For the biochemical assay panel, 50 nl of the test compounds, reference compounds and buffer/DMSO control are transferred to the respective wells of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent