BDBM23926 (E)-resveratrol::5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol::CHEMBL165::Resveratol::Stilbene, 2f::US11866416, Example 7::cid_445154::resveratrol::trans-resveratrol
SMILES Oc1ccc(\C=C\c2cc(O)cc(O)c2)cc1
InChI Key InChIKey=LUKBXSAWLPMMSZ-OWOJBTEDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 167 hits for monomerid = 23926
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 88nMAssay Description:Competitive inhibition of human quinone reductase 2 using menadione/N-methyldihydronicotinamide as substrate after 10 mins by double-reciprocal plot ...More data for this Ligand-Target Pair
Affinity DataKi: 169nM ΔG°: -8.58kcal/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
Affinity DataKi: 177nM ΔG°: -9.58kcal/molepH: 8.0 T: 2°CAssay Description:The ethoxyresorufin-O-deethylase (EROD) assay is used to test the activity of CYP1B1. More data for this Ligand-Target Pair
Affinity DataKi: 750nMAssay Description:Mixed type inhibition of human CYP1B1 by EROD assayMore data for this Ligand-Target Pair
Affinity DataKi: 785nMAssay Description:Cytosols from MCF-7 cells expressed ER-alpha isoform were incubated with [3H]-estradiol and eight concentrations of unlabeled test ligands. IC50 val...More data for this Ligand-Target Pair
Affinity DataKi: 800nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in supersomes coexpressing NADPH-CYP reductase using 7-ethoxyresorufin as substrate after 15 mins in...More data for this Ligand-Target Pair
Affinity DataKi: 810nMAssay Description:Inhibition of human carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 830nMAssay Description:Inhibition of human carbonic anhydrase 14 after 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 950nMAssay Description:Inhibition of human carbonic anhydrase 12 after 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.75E+3nMAssay Description:Inhibition of cytosolic human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.95E+3nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.18E+3nMAssay Description:Inhibition of cytosolic human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.21E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.57E+3nMAssay Description:Inhibition of mouse carbonic anhydrase 15 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.77E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.86E+3nMAssay Description:Inhibition of human carbonic anhydrase 5a preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.24E+3nMAssay Description:Inhibition of human carbonic anhydrase 5b preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.01E+3nMAssay Description:Inhibition of human carbonic anhydrase 4 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.09E+3nMAssay Description:Inhibition of human carbonic anhydrase 13 after 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 4.35E+3nMAssay Description:Inhibition of human carbonic anhydrase 7 after 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 4.47E+3nMAssay Description:Inhibition of human carbonic anhydrase 4 after 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 4.64E+3nMAssay Description:Inhibition of human carbonic anhydrase 5b after 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 4.75E+3nMAssay Description:Inhibition of human carbonic anhydrase 5a after 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 6.75E+3nMAssay Description:Inhibition of human carbonic anhydrase 3 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.07E+3nMAssay Description:Inhibition of human carbonic anhydrase 6 after 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 8.13E+3nMAssay Description:Inhibition of transmembrane tumor-associated human carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.25E+3nMAssay Description:Inhibition of human carbonic anhydrase 13 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.63E+3nMAssay Description:Inhibition of human carbonic anhydrase 6 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.98E+3nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.09E+3nMAssay Description:Inhibition of human carbonic anhydrase 3 after 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 9.36E+3nMAssay Description:Inhibition of mouse carbonic anhydrase 15 after 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 9.53E+3nMAssay Description:Inhibition of transmembrane tumor-associated human carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
St. Bartholomew'S And The Royal London School Of Medicine And Dentistry
Curated by PDSP Ki Database
St. Bartholomew'S And The Royal London School Of Medicine And Dentistry
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
St. Bartholomew'S And The Royal London School Of Medicine And Dentistry
Curated by PDSP Ki Database
St. Bartholomew'S And The Royal London School Of Medicine And Dentistry
Curated by PDSP Ki Database
Affinity DataKi: 1.12E+4nMAssay Description:Inhibition of CYP1B1 in TCDD-exposed human MCF-7 cells using ethoxyresorufin as substrate after 20 mins in presence of NADPH by Lineweaver-Burk linea...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Mechanism based inhibition of human cytochrome P450 3A4 measured by testosterone 6-beta hydroxylationMore data for this Ligand-Target Pair
Affinity DataKi: 2.15E+4nM IC50: 2.64E+4nMAssay Description:All enzymatic activities were determined by using the appropriate substrate (p-nitrophenyl-alpha-D-glucopyranoside, p-nitrophenyl-beta-D-gulcopyranos...More data for this Ligand-Target Pair
Affinity DataKi: 4.17E+4nMAssay Description:Competitive inhibition of human aromatase using dibenzylfluorescein substrate after 10 mins preincubation measured every 10 sec for 5 mins by Michael...More data for this Ligand-Target Pair
Affinity DataKi: 2.90E+6nMAssay Description:Inhibition of tyrosinase in mouse Melan-a cells assessed as decrease in L-DOPA Vmax at 120 uM by Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: 960nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: 960nMpH: 8.0 T: 2°CAssay Description:The activity of recombinant human QR2 under steady-state conditions was evaluated on a MolecularDevices SpectraMax Plus 384 UV-visible spectrophotome...More data for this Ligand-Target Pair
Affinity DataEC50: 5.20E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+5nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
Affinity DataEC50: 1.63E+5nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
TargetM18 aspartyl aminopeptidase(Plasmodium falciparum 3D7)
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 2.24E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
TargetProcathepsin L(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: >5.96E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center
Curated by PubChem BioAssay
Southern Research Specialized Biocontainment Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 2.62E+4nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 33(Homo sapiens (Human))
Broad Institute
Curated by PubChem BioAssay
Broad Institute
Curated by PubChem BioAssay
Affinity DataEC50: 1.23E+4nMAssay Description:Keywords: STK33 Kinase, Non-ATP Competitive Inhibitor Assay Overview: Purified STK33 Kinase is preincubated with potential inhibitors and allowed to ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:The actual target(s) whereby the most active substituted trans-stilbenes inhibit the TNFα-induced activation of NF-κB remains to be identif...More data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+4nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 1 hit for monomerid = 23926
ITC DataΔG°: -9.78kcal/mole −TΔS°: 5.00kcal/mole ΔH°: -14.6kcal/mole logk: 2.56E+7
pH: 7.5 T: 25.00°C
pH: 7.5 T: 25.00°C