BDBM23987 2-hydroxy-1,2,3,4-tetrahydroisoquinolin-3-one::CHEMBL16419::N-Substituted dihydro-isoquinolinone, 4c

SMILES ON1Cc2ccccc2CC1=O

InChI Key InChIKey=YOZVVRFEIGPQPK-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 23987   

TargetBacterial leucyl aminopeptidase(Vibrio proteolyticus)
Enscmu

LigandPNGBDBM23987(2-hydroxy-1,2,3,4-tetrahydroisoquinolin-3-one | CH...)
Affinity DataKi:  4.00E+3nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolymerase acidic protein(Hepatitis C virus)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM23987(2-hydroxy-1,2,3,4-tetrahydroisoquinolin-3-one | CH...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibitory concentration against cap-dependent endonuclease activity of influenza virus RNPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Enscmu

LigandPNGBDBM23987(2-hydroxy-1,2,3,4-tetrahydroisoquinolin-3-one | CH...)
Affinity DataIC50: >1.00E+6nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Bos taurus (bovine))
Enscmu

LigandPNGBDBM23987(2-hydroxy-1,2,3,4-tetrahydroisoquinolin-3-one | CH...)
Affinity DataIC50: >1.00E+6nMpH: 8.0 T: 2°CAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
Enscmu

LigandPNGBDBM23987(2-hydroxy-1,2,3,4-tetrahydroisoquinolin-3-one | CH...)
Affinity DataIC50: >1.00E+6nMAssay Description:Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed