BDBM24508 3-(3-fluoro-4-{[2-(1,3,4-thiadiazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-(2-phenylacetyl)thiourea::thieno[3,2-b]pyridine-based inhibitor, 10k

SMILES Fc1cc(NC(=S)NC(=O)Cc2ccccc2)ccc1Oc1ccnc2cc(sc12)-c1nncs1

InChI Key InChIKey=JVYQBIGQNUDXIK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 24508   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

LigandPNGBDBM24508(3-(3-fluoro-4-{[2-(1,3,4-thiadiazol-2-yl)thieno[3,...)
Affinity DataIC50:  60nMpH: 7.5 T: 2°CAssay Description:Inhibition of kinase activity was measured in a DELFIA assay (Perkin-Elmer). The substrate poly (Glu4, Tyr) was immobilized onto black high-binding p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

LigandPNGBDBM24508(3-(3-fluoro-4-{[2-(1,3,4-thiadiazol-2-yl)thieno[3,...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Methylgene

LigandPNGBDBM24508(3-(3-fluoro-4-{[2-(1,3,4-thiadiazol-2-yl)thieno[3,...)
Affinity DataIC50:  145nMAssay Description:Inhibition of kinase activity was measured in a DELFIA assay (Perkin-Elmer). The substrate poly (Glu4, Tyr) was immobilized onto black high-binding p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed