BDBM24516 (2E,5E)-5-[(4-methoxyphenyl)methylidene]-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-one::Thiazole analogue, 3
SMILES COc1ccc(\C=C2\S\C(NC2=O)=N\c2nccs2)cc1
InChI Key InChIKey=VFGDMNZKSPCGCZ-DHZHZOJOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 24516
Affinity DataKi: 1.17E+4nM ΔG°: -6.72kcal/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Alexander Technological Education Institute Of Thessaloniki
Curated by ChEMBL
Alexander Technological Education Institute Of Thessaloniki
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassayMore data for this Ligand-Target Pair