BDBM247150 (S,E)-2-Methyl-N-(2,2,2-trifluoro-1-(4-((5,5,5-trifluoropentyl)oxy phenyl)ethylidene)propane-2-sulfinamide::US9701672, 4::US9701672, 54

SMILES Fc1cc(OCCCC(F)(F)F)ccc1[C@@]1(CC(c2ccc(s2)C2CC2)=C(c2nnn[nH]2)C(=O)N1)C(F)(F)F

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 247150   

TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM247150((S,E)-2-Methyl-N-(2,2,2-trifluoro-1-(4-((5,5,5-tri...)
Affinity DataIC50:  0.900nMpH: 7.4Assay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM247150((S,E)-2-Methyl-N-(2,2,2-trifluoro-1-(4-((5,5,5-tri...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant human MGAT2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM247150((S,E)-2-Methyl-N-(2,2,2-trifluoro-1-(4-((5,5,5-tri...)
Affinity DataIC50:  1.10nMpH: 7.4Assay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent