BDBM25739 4-({4-[(adamantan-1-ylcarbamoyl)amino]cyclohexyl}oxy)benzoic acid::US10383835, Compound 1471::Urea-based compound, 20::Urea-based compound, 21

SMILES OC(=O)c1ccc(OC2CCC(CC2)NC(=O)NC23CC4CC(CC(C4)C2)C3)cc1

InChI Key InChIKey=KNBWKJBQDAQARU-UHFFFAOYSA-N

Data  7 IC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 25739   

TargetEpoxide hydrolase B(Mycobacterium tuberculosis)
University Of Alberta

LigandPNGBDBM25739(4-({4-[(adamantan-1-ylcarbamoyl)amino]cyclohexyl}o...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpoxide hydrolase B(Mycobacterium tuberculosis)
University Of Alberta

LigandPNGBDBM25739(4-({4-[(adamantan-1-ylcarbamoyl)amino]cyclohexyl}o...)
Affinity DataIC50:  3.40E+3nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpoxide hydrolase(Equus caballus (Horse))
The Regents Of The University Of California

US Patent
LigandPNGBDBM25739(4-({4-[(adamantan-1-ylcarbamoyl)amino]cyclohexyl}o...)
Affinity DataIC50:  10nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpoxide hydrolase 1(Canis lupus familiaris (Dog) (Canis familiaris))
The Regents Of The University Of California

US Patent
LigandPNGBDBM25739(4-({4-[(adamantan-1-ylcarbamoyl)amino]cyclohexyl}o...)
Affinity DataIC50:  1nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Sus scrofa (Pig))
The Regents Of The University Of California

US Patent
LigandPNGBDBM25739(4-({4-[(adamantan-1-ylcarbamoyl)amino]cyclohexyl}o...)
Affinity DataIC50:  8nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpoxide hydrolase 1(Felis catus (Cat) (Felis silvestris catus))
The Regents Of The University Of California

US Patent
LigandPNGBDBM25739(4-({4-[(adamantan-1-ylcarbamoyl)amino]cyclohexyl}o...)
Affinity DataIC50:  6nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpoxide hydrolase(Ovis aries (Sheep))
The Regents Of The University Of California

US Patent
LigandPNGBDBM25739(4-({4-[(adamantan-1-ylcarbamoyl)amino]cyclohexyl}o...)
Affinity DataIC50:  5nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In DepthDetails US Patent