BDBM26109 Butyrate::butanoic acid::butanoic acid, 4
SMILES CCCC(O)=O
InChI Key InChIKey=FERIUCNNQQJTOY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 26109
Affinity DataKi: 8.20E+4nMAssay Description:Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 1.36E+5nMAssay Description:Inhibition of HDAC in human Hela cells nuclear extracts by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.50E+6nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant HDAC8More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of human recombinant HDAC4More data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of human recombinant HDAC5More data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of human recombinant HDAC7More data for this Ligand-Target Pair
TargetHistone deacetylase 9(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of human recombinant HDAC9More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+4nMAssay Description:Agonist activity at human GPCR41 transfected in HEK293 cells assessed as [35S]GTPgammaS binding by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+7nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
TargetMethyl-accepting chemotaxis protein NahY(Pseudomonas putida (Arthrobacter siderocapsulatus))
Csic
Csic
Affinity DataKd: 9.20E+4nMT: 2°CAssay Description:Measurements were done on a VP-microcalorimeter (MicroCal, Amherst, MA).More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 1 hit for monomerid = 26109
CellMethyl-accepting chemotaxis protein (McpS)(Pseudomonas putida (Arthrobacter siderocapsulatus))
Csic
Csic
ITC DataΔG°: -5.41kcal/mole −TΔS°: 2.80kcal/mole ΔH°: -7.88kcal/mole logk: 1.09E+4
T: 20.00°C
T: 20.00°C