BDBM26265 (5S)-6-(5-chloropyridin-2-yl)-7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate::ESZ::Estorra::Eszopiclone::Lunesta::cid_5735
SMILES CN1CCN(CC1)C(=O)Oc1n(-c2ccc(Cl)cn2)c(=O)c2ncc[nH]c12
InChI Key InChIKey=DZCUZLPTNNFSNM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 29 hits for monomerid = 26265
TargetGamma-aminobutyric acid receptor subunit alpha-1 [T206C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 0.830nM ΔG°: -12.4kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-200],P14867[176-456](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 22.4nM ΔG°: -10.4kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [T162C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 33.8nM ΔG°: -10.2kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [S205C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 34.9nM ΔG°: -10.2kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,L179C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 46.3nM ΔG°: -10.0kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 50.1nM ΔG°: -9.85kcal/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [S204C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 57.9nM ΔG°: -9.87kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [A160C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 60.4nM ΔG°: -9.84kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [V211C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 62.4nM ΔG°: -9.82kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,R233C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 67nM ΔG°: -9.78kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,R224C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 70.9nM ΔG°: -9.75kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,T165C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 71.9nM ΔG°: -9.74kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,T120C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 75.2nM ΔG°: -9.71kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,D95C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 82.4nM ΔG°: -9.66kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 102nM ΔG°: -9.44kcal/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,M169C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 102nM ΔG°: -9.53kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,R171C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 110nM ΔG°: -9.49kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2 [29-451]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 114nM ΔG°: -9.37kcal/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [G200C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 119nM ΔG°: -9.44kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3 [29-492]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 162nM ΔG°: -9.16kcal/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,R183C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 174nM ΔG°: -9.21kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [V202C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 249nM ΔG°: -9.00kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,A118C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 393nM ΔG°: -8.73kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [F99C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 407nM ΔG°: -8.62kcal/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,T181C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 503nM ΔG°: -8.59kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [G157C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 2.10E+3nM ΔG°: -7.74kcal/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4 [36-554]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: >1.50E+4nM ΔG°: >-6.51kcal/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6 [20-453]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: >1.50E+4nM ΔG°: >-6.51kcal/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: >4.98E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair