BDBM273138 (R)-N-benzyl-2-{N'-[5-(2-fluorophenyl)-7-oxo-6,7-dihydro[1,3]thiazolo[5,4-d]pyrimidin-2-yl]-N'-methylamino}propionamide::US10065972, Example 532

SMILES C[C@@H](N(C)c1nc2c(nc([nH]c2=O)-c2ccccc2F)s1)C(=O)NCc1ccccc1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273138   

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM273138((R)-N-benzyl-2-{N'-[5-(2-fluorophenyl)-7-oxo-6,7-d...)
Affinity DataIC50:  17nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent