BDBM276752 2-(5-((3-ethoxypyridin- 2-yl)oxy)pyridin-3-yl)-N-(3- methyl-1,1-dioxidotetra- hydrothiophen-3-yl) pyrimidine-5-carboxamide::US10071992, Example 3.1::US11034678, Example 3.1::US11065249, WO2018033832-Ex.-3.1::WO2018033832, Ex. 3.1

SMILES CCOc1cccnc1Oc1cncc(c1)-c1ncc(cn1)C(=O)NC1(C)CCS(=O)(=O)C1

InChI Key InChIKey=QTACEBNHAXTZEN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 276752   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM276752(2-(5-((3-ethoxypyridin- 2-yl)oxy)pyridin-3-yl)-N-(...)
Affinity DataIC50:  13.5nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 1 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM276752(2-(5-((3-ethoxypyridin- 2-yl)oxy)pyridin-3-yl)-N-(...)
Affinity DataIC50:  13nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM276752(2-(5-((3-ethoxypyridin- 2-yl)oxy)pyridin-3-yl)-N-(...)
Affinity DataIC50:  13.5nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 1 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM276752(2-(5-((3-ethoxypyridin- 2-yl)oxy)pyridin-3-yl)-N-(...)
Affinity DataIC50:  13nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent