BDBM27726 (2S,3R)-3-(tert-butoxy)-2-[(3-{[(2,4,6-trimethylphenyl)carbamoyl]amino}naphthalen-2-yl)formamido]butanoic acid::CHEMBL473851::anthranilimide based compound, 2

SMILES C[C@@H](OC(C)(C)C)[C@H](NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C)C(O)=O

InChI Key InChIKey=SIVVDUDKHBTSKI-CLOONOSVSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 27726   

TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Gsk

LigandPNGBDBM27726((2S,3R)-3-(tert-butoxy)-2-[(3-{[(2,4,6-trimethylph...)
Affinity DataIC50:  7nMpH: 7.6 T: 2°CAssay Description:An enzymatic assay was developed to measure the response of the activated form of glycogen phosphorylase to small molecule compounds. The assay was t...More data for this Ligand-Target Pair
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Gsk

LigandPNGBDBM27726((2S,3R)-3-(tert-butoxy)-2-[(3-{[(2,4,6-trimethylph...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human liver glycogen phosphorylase A by fluorescence plate reader assayMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM27726((2S,3R)-3-(tert-butoxy)-2-[(3-{[(2,4,6-trimethylph...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Gsk

LigandPNGBDBM27726((2S,3R)-3-(tert-butoxy)-2-[(3-{[(2,4,6-trimethylph...)
Affinity DataIC50:  139nMAssay Description:Inhibition of liver glycogen phosphorylase A in human HepG2 cells assessed as inhibition of forskolin-induced glucogenolysisMore data for this Ligand-Target Pair