BDBM281180 US10022354, Example 120

SMILES CC(C)c1cc([nH]n1)C(=O)N1CCC(C1)NC(=O)c1ccc2cc[nH]c2c1

InChI Key InChIKey=QHEGYMNPXHQSPZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 281180   

TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM281180(US10022354, Example 120)
Affinity DataIC50:  0.0530nMpH: 7.0 T: 2°CAssay Description:Full length KDM5A enzyme was expressed and purified inhouse. Biotin-H3K4me3 peptide was purchased from New England Biolabs. HTRF reagents (containing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent