BDBM281802 N-(1-(3,4-difluorophenyl)ethyl)- 2-(((5-(1-methyl-1H-imidazo[4,5-c] quinolin-8-yl)thiophen-2-yl)methyl) amino)nicotinamide::US10030016, Example 2.24

SMILES Cn1cnc2cnc3ccc(cc3c12)-c1ccc(CNc2ncccc2C(=O)NCc2ccc(F)c(F)c2)s1

InChI Key InChIKey=ZLARKOCDKIRYTA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 281802   

Target3-phosphoinositide-dependent protein kinase 1 [51-359](Homo sapiens (Human))
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM281802(N-(1-(3,4-difluorophenyl)ethyl)- 2-(((5-(1-methyl-...)
Affinity DataIC50: <100nMAssay Description:PDK1 (amino acids 51-359) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) were expressed as N-terminally tagged GST fusi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent