BDBM281903 N-cyclopropyl-3-{3- [({3-[(3-fluorobenzyl) carbamoyl]pyridin- 2-yl}amino)methyl]- 5-(propan-2-yloxy) phenyl}-1H-pyrrolo [2,3-b]pyridine-5- carboxamide::US10030016, Example 4.1.4
SMILES CC(C)Oc1cc(CNc2ncccc2C(=O)NCc2cccc(F)c2)cc(c1)-c1c[nH]c2ncc(cc12)C(=O)NC1CC1
InChI Key InChIKey=JMMRKLZREOQGDF-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 281903
Target3-phosphoinositide-dependent protein kinase 1 [51-359](Homo sapiens (Human))
Sunesis Pharmaceuticals
US Patent
Sunesis Pharmaceuticals
US Patent
Affinity DataIC50: <100nMAssay Description:PDK1 (amino acids 51-359) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) were expressed as N-terminally tagged GST fusi...More data for this Ligand-Target Pair