BDBM290384 (3R,4S)-1-((1H-imidazol-4-yl)methyl)-3-amino-4-(3- boronopropyl)pyrrolidine-3-carboxylic acid::US10098902, Example 20::US11389464, Example 20

SMILES N[C@]1(CN(Cc2c[nH]cn2)C[C@@H]1CCCB(O)O)C(O)=O

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 290384   

TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290384((3R,4S)-1-((1H-imidazol-4-yl)methyl)-3-amino-4-(3-...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290384((3R,4S)-1-((1H-imidazol-4-yl)methyl)-3-amino-4-(3-...)
Affinity DataIC50:  625nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290384((3R,4S)-1-((1H-imidazol-4-yl)methyl)-3-amino-4-(3-...)
Affinity DataIC50:  125nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290384((3R,4S)-1-((1H-imidazol-4-yl)methyl)-3-amino-4-(3-...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent