BDBM290430 (1S,2S,4R)-1-amino-4-(2-aminoethyl)-2-(3- boronopropyl)cyclopentanecarboxylic acid::US10098902, Example 66::US10603330, Example 661::US11389464, Example 66

SMILES NCC[C@H]1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O

InChI Key InChIKey=JMEAANQEVQQZDI-QXEWZRGKSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 290430   

TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290430((1S,2S,4R)-1-amino-4-(2-aminoethyl)-2-(3- boronopr...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290430((1S,2S,4R)-1-amino-4-(2-aminoethyl)-2-(3- boronopr...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290430((1S,2S,4R)-1-amino-4-(2-aminoethyl)-2-(3- boronopr...)
Affinity DataIC50:  125nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290430((1S,2S,4R)-1-amino-4-(2-aminoethyl)-2-(3- boronopr...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290430((1S,2S,4R)-1-amino-4-(2-aminoethyl)-2-(3- boronopr...)
Affinity DataIC50:  125nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290430((1S,2S,4R)-1-amino-4-(2-aminoethyl)-2-(3- boronopr...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent