BDBM29613 2-Imino-1-(4-methyl-benzyl)-10-oxo-1,10-dihydro-2H-1,9,10a-triaza-anthracene-3-carboxylic acid (furan-2-ylmethyl)-amide::2-azanylidene-N-(furan-2-ylmethyl)-1-[(4-methylphenyl)methyl]-5-oxidanylidene-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide::MLS000075054::N-(2-furanylmethyl)-2-imino-1-[(4-methylphenyl)methyl]-5-oxo-3-dipyrido[1,2-d:3',4'-f]pyrimidinecarboxamide::N-(2-furfuryl)-2-imino-5-keto-1-(4-methylbenzyl)dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide::N-(furan-2-ylmethyl)-2-imino-1-[(4-methylphenyl)methyl]-5-oxodipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide::SMR000013488::cid_644735

SMILES Cc1ccc(Cn2c3nc4ccccn4c(=O)c3cc(C(=O)NCc3ccco3)c2=N)cc1

InChI Key InChIKey=MWQOUSHKYPZGHQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 29613   

TargetRunt-related transcription factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29613(2-Imino-1-(4-methyl-benzyl)-10-oxo-1,10-dihydro-2H...)
Affinity DataIC50:  1.53E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetKallikrein-5(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM29613(2-Imino-1-(4-methyl-benzyl)-10-oxo-1,10-dihydro-2H...)
Affinity DataIC50:  5.00E+4nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM29613(2-Imino-1-(4-methyl-benzyl)-10-oxo-1,10-dihydro-2H...)
Affinity DataIC50:  3.14E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29613(2-Imino-1-(4-methyl-benzyl)-10-oxo-1,10-dihydro-2H...)
Affinity DataIC50:  1.53E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay