BDBM29621 1-benzyl-2-(2-furoylamino)-N-(3-methoxypropyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide::1-benzyl-2-(furan-2-carbonylamino)-N-(3-methoxypropyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide::2-(furan-2-ylcarbonylamino)-N-(3-methoxypropyl)-1-(phenylmethyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide::2-[[2-furanyl(oxo)methyl]amino]-N-(3-methoxypropyl)-1-(phenylmethyl)-3-pyrrolo[3,2-b]quinoxalinecarboxamide::MLS000037080::SMR000040504::cid_659456

SMILES COCCCNC(=O)c1c(NC(=O)c2ccco2)n(Cc2ccccc2)c2nc3ccccc3nc12

InChI Key InChIKey=DHDVVMIYKAPBOC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 29621   

TargetRunt-related transcription factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29621(1-benzyl-2-(2-furoylamino)-N-(3-methoxypropyl)pyrr...)
Affinity DataIC50:  1.60E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetApoptotic protease-activating factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29621(1-benzyl-2-(2-furoylamino)-N-(3-methoxypropyl)pyrr...)
Affinity DataIC50: >1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetApoptotic protease-activating factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29621(1-benzyl-2-(2-furoylamino)-N-(3-methoxypropyl)pyrr...)
Affinity DataIC50: >1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29621(1-benzyl-2-(2-furoylamino)-N-(3-methoxypropyl)pyrr...)
Affinity DataIC50:  1.60E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay