BDBM29638 1-[4-(2-furoyl)piperazino]-3-isopropyl-pyrido[1,2-a]benzimidazole-4-carbonitrile::1-[4-(furan-2-carbonyl)piperazin-1-yl]-3-propan-2-ylpyrido[1,2-a]benzimidazole-4-carbonitrile::1-[4-(furan-2-ylcarbonyl)piperazin-1-yl]-3-propan-2-yl-pyrido[1,2-a]benzimidazole-4-carbonitrile::1-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]-3-propan-2-yl-4-pyrido[1,2-a]benzimidazolecarbonitrile::MLS000103510::SMR000018805::cid_1284208

SMILES CC(C)c1cc(N2CCN(CC2)C(=O)c2ccco2)n2c3ccccc3nc2c1C#N

InChI Key InChIKey=SIVCAUIKASCNMM-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29638   

TargetRunt-related transcription factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29638(1-[4-(2-furoyl)piperazino]-3-isopropyl-pyrido[1,2-...)
Affinity DataIC50:  1.00E+5nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetImportin subunit alpha-1(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM29638(1-[4-(2-furoyl)piperazino]-3-isopropyl-pyrido[1,2-...)
Affinity DataEC50:  1.61E+4nMAssay Description:Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29638(1-[4-(2-furoyl)piperazino]-3-isopropyl-pyrido[1,2-...)
Affinity DataIC50:  1.00E+5nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay