BDBM29675 2-methyl-N-(4-thiazolo[5,4-b]pyridin-2-ylphenyl)-1,3-benzothiazole-6-sulfonamide::2-methyl-N-[4-(2-thiazolo[5,4-b]pyridinyl)phenyl]-1,3-benzothiazole-6-sulfonamide::2-methyl-N-[4-([1,3]thiazolo[5,4-b]pyridin-2-yl)phenyl]-1,3-benzothiazole-6-sulfonamide::MLS000696611::SMR000235790::cid_12006124

SMILES Cc1nc2ccc(cc2s1)S(=O)(=O)Nc1ccc(cc1)-c1nc2cccnc2s1

InChI Key InChIKey=MDIUHSXLUNWCLE-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 29675   

TargetRunt-related transcription factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29675(2-methyl-N-(4-thiazolo[5,4-b]pyridin-2-ylphenyl)-1...)
Affinity DataIC50:  1.00E+5nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetImportin subunit alpha-1(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM29675(2-methyl-N-(4-thiazolo[5,4-b]pyridin-2-ylphenyl)-1...)
Affinity DataEC50:  3.85E+4nMAssay Description:Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29675(2-methyl-N-(4-thiazolo[5,4-b]pyridin-2-ylphenyl)-1...)
Affinity DataIC50:  1.00E+5nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29675(2-methyl-N-(4-thiazolo[5,4-b]pyridin-2-ylphenyl)-1...)
Affinity DataIC50:  713nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay