BDBM298377 US10124003, Ex. Compound 55::US10835536, Ex. Comp 55

SMILES COc1cc(OC)cc(c1)C#Cc1cn(C2CN(C2)C(=O)\C=C\CN2CCC2)c2ncnc(N)c12

InChI Key InChIKey=LJEXNLQQUUZCQM-HWKANZROSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 298377   

TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM298377(US10124003, Ex. Compound 55 | US10835536, Ex. Comp...)
Affinity DataIC50:  2.5nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM298377(US10124003, Ex. Compound 55 | US10835536, Ex. Comp...)
Affinity DataIC50:  2.5nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent