BDBM30027 BMCL181297 Compound 5A::cid_662965::triazolothiadiazine, 21

SMILES COc1ccc(cc1OC)C1=Nn2c(SC1)nnc2-c1ccccc1OC

InChI Key InChIKey=SMOWDUACKVMUAN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 30027   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
National Human Genome Research Institute

LigandPNGBDBM30027(BMCL181297 Compound 5A | cid_662965 | triazolothia...)
Affinity DataIC50:  46nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
National Human Genome Research Institute

LigandPNGBDBM30027(BMCL181297 Compound 5A | cid_662965 | triazolothia...)
Affinity DataIC50:  40nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroidogenic factor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM30027(BMCL181297 Compound 5A | cid_662965 | triazolothia...)
Affinity DataIC50: >3.67E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetIsoform 2 of Nuclear receptor ROR-alpha (Alpha-2)(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM30027(BMCL181297 Compound 5A | cid_662965 | triazolothia...)
Affinity DataIC50:  9.01E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM30027(BMCL181297 Compound 5A | cid_662965 | triazolothia...)
Affinity DataIC50: >5.53E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay