BDBM3072 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 39::6-(2,6-dichlorophenyl)-8-ethyl-2-(phenylamino)-7H,8H-pyrido[2,3-d]pyrimidin-7-one::PD 166285 analog

SMILES CCn1c2nc(Nc3ccccc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O

InChI Key InChIKey=XZBKAAPFQAVYSN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 3072   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3072(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 39 | 6-(2,...)
Affinity DataIC50:  800nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3072(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 39 | 6-(2,...)
Affinity DataIC50:  200nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3072(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 39 | 6-(2,...)
Affinity DataIC50:  53nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3072(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 39 | 6-(2,...)
Affinity DataIC50:  210nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed