BDBM30741 2-amino-6-(4-chlorophenyl)-4-(5-methyl-3-furanyl)-3-pyridinecarbonitrile::2-amino-6-(4-chlorophenyl)-4-(5-methyl-3-furyl)nicotinonitrile::2-amino-6-(4-chlorophenyl)-4-(5-methylfuran-3-yl)pyridine-3-carbonitrile::2-azanyl-6-(4-chlorophenyl)-4-(5-methylfuran-3-yl)pyridine-3-carbonitrile::MLS000036685::SMR000041039::cid_660120

SMILES Cc1cc(co1)-c1cc(nc(N)c1C#N)-c1ccc(Cl)cc1

InChI Key InChIKey=ULMVEMLCXMFMMN-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 30741   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM30741(2-amino-6-(4-chlorophenyl)-4-(5-methyl-3-furanyl)-...)
Affinity DataEC50:  9.90E+4nMpH: 7.4 T: 2°CAssay Description:A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-related protein A1(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM30741(2-amino-6-(4-chlorophenyl)-4-(5-methyl-3-furanyl)-...)
Affinity DataEC50:  4.92E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 10 [11-204](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM30741(2-amino-6-(4-chlorophenyl)-4-(5-methyl-3-furanyl)-...)
Affinity DataEC50:  1.52E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-related protein A1(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM30741(2-amino-6-(4-chlorophenyl)-4-(5-methyl-3-furanyl)-...)
Affinity DataEC50:  3.86E+3nMpH: 7.4 T: 2°CAssay Description:The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay