BDBM31047 (5-Phenylsulfanyl-1H-benzoimidazol-2-yl)-carbamic acid methyl ester::CHEMBL37161::FENBENDAZOLE::MLS000069723::N-[6-(phenylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester::SMR000058217::cid_3334::methyl 5-(phenylthio)-1H-benzo[d]imidazol-2-ylcarbamate::methyl N-(6-phenylsulfanyl-1H-benzimidazol-2-yl)carbamate

SMILES COC(=O)Nc1nc2ccc(Sc3ccccc3)cc2[nH]1

InChI Key InChIKey=HDDSHPAODJUKPD-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 31047   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM31047((5-Phenylsulfanyl-1H-benzoimidazol-2-yl)-carbamic ...)
Affinity DataIC50:  4.00E+4nMpH: 7.4 T: 2°CAssay Description:A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
Target5-hydroxytryptamine receptor 1E(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM31047((5-Phenylsulfanyl-1H-benzoimidazol-2-yl)-carbamic ...)
Affinity DataIC50:  5.00E+4nMpH: 7.4 T: 2°CAssay Description:To measure 5-HT1E activity, a Chinese Hamster Ovary (CHO) cell line was developed at the Scripps Molecular Research Institute Screening center. This ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNuclear receptor subfamily 1 group I member 2(Rattus norvegicus)
National Institutes Of Health Chemical Genomics Center

Curated by ChEMBL
LigandPNGBDBM31047((5-Phenylsulfanyl-1H-benzoimidazol-2-yl)-carbamic ...)
Affinity DataEC50:  4.00E+3nMAssay Description:Activation of rat PXR expressed in human HepG2 cells after 24 hrs by luciferase reporter gene based luminescent analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase(Escherichia coli (strain K12))
Saarland University

Curated by ChEMBL
LigandPNGBDBM31047((5-Phenylsulfanyl-1H-benzoimidazol-2-yl)-carbamic ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Co2+ loaded MetAP expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
National Institutes Of Health Chemical Genomics Center

Curated by ChEMBL
LigandPNGBDBM31047((5-Phenylsulfanyl-1H-benzoimidazol-2-yl)-carbamic ...)
Affinity DataEC50:  1.00E+4nMAssay Description:Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM31047((5-Phenylsulfanyl-1H-benzoimidazol-2-yl)-carbamic ...)
Affinity DataIC50: >5.00E+4nMAssay Description:External Assay ID: S1P3_IC50_CS_5H1E_Antagonists Name: S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay