BDBM31223 2-phenoxybenzoyltryptophan derivative, R5C1

SMILES Cc1ccc2[nH]cc(C[C@H](NC(=O)c3ccccc3Oc3ccccc3)C(O)=O)c2c1

InChI Key InChIKey=WGSQKPIUJIOGOT-QFIPXVFZSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31223   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM31223(2-phenoxybenzoyltryptophan derivative, R5C1)
Affinity DataKi:  1.00E+4nM ΔG°:  -6.77kcal/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed