BDBM312500 4-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-4,5,6,7-tetrahydro-benzo[b]thiophen-2-ylcarbamoyl]-5,6-dihydro-2H-pyran-3-carboxylic acid::US9604977, Example 246

SMILES OC(=O)C1=C(CCOC1)C(=O)Nc1sc2CCCCc2c1-c1nc(no1)C1CC1

InChI Key InChIKey=SDROMBPMGRXOSJ-UHFFFAOYSA-N

Data  2 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312500   

TargetFatty acid-binding protein 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM312500(4-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-4,5,6,7...)
Affinity DataIC50:  120nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM312500(4-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-4,5,6,7...)
Affinity DataIC50:  17nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB