BDBM314100 3-[(4-fluorobenzyl)amino]pyridine-4-carboxylic acid::US10179769, Example 4::US10807956, Example 4::US11214542, Example 4::US11639333, Example 4::US9611221, Example 4::US9725441, Example 4::US9828343, Example 4

SMILES OC(=O)c1ccncc1NCc1ccc(F)cc1

InChI Key InChIKey=LEJXPLDUYCZSQX-UHFFFAOYSA-N

Data  9 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 314100   

TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM314100(3-[(4-fluorobenzyl)amino]pyridine-4-carboxylic aci...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM314100(3-[(4-fluorobenzyl)amino]pyridine-4-carboxylic aci...)
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM314100(3-[(4-fluorobenzyl)amino]pyridine-4-carboxylic aci...)
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM314100(3-[(4-fluorobenzyl)amino]pyridine-4-carboxylic aci...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM314100(3-[(4-fluorobenzyl)amino]pyridine-4-carboxylic aci...)
Affinity DataIC50: <100nMAssay Description:JMJD2C: The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM314100(3-[(4-fluorobenzyl)amino]pyridine-4-carboxylic aci...)
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM314100(3-[(4-fluorobenzyl)amino]pyridine-4-carboxylic aci...)
Affinity DataIC50: <100nMAssay Description:Jarid1A: The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM314100(3-[(4-fluorobenzyl)amino]pyridine-4-carboxylic aci...)
Affinity DataIC50: <100nMAssay Description:Jarid1B: The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction condit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM314100(3-[(4-fluorobenzyl)amino]pyridine-4-carboxylic aci...)
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent